Elevated plasma sTIM-3 levels in patients with severe COVID-19
T Ueland, L Heggelund, A Lind, AR Holten… - Journal of Allergy and …, 2021 - Elsevier
Background The pathogenesis of coronavirus disease 2019 (COVID-19) is still incompletely
understood, but it seems to involve immune activation and immune dysregulation. Objective
We examined the parameters of activation of different leukocyte subsets in COVID-19–
infected patients in relation to disease severity. Methods We analyzed plasma levels of
myeloperoxidase (a marker of neutrophil activation), soluble (s) CD25 (sCD25) and soluble
T-cell immunoglobulin mucin domain-3 (sTIM-3)(markers of T-cell activation and …
understood, but it seems to involve immune activation and immune dysregulation. Objective
We examined the parameters of activation of different leukocyte subsets in COVID-19–
infected patients in relation to disease severity. Methods We analyzed plasma levels of
myeloperoxidase (a marker of neutrophil activation), soluble (s) CD25 (sCD25) and soluble
T-cell immunoglobulin mucin domain-3 (sTIM-3)(markers of T-cell activation and …