Dentin matrix protein 1 immobilized on type I collagen fibrils facilitates apatite deposition in vitro
G He, A George - Journal of Biological Chemistry, 2004 - ASBMB
During bone and dentin mineralization, the crystal nucleation and growth processes are
considered to be matrix regulated. Osteoblasts and odontoblasts synthesize a polymeric
collagenous matrix, which forms a template for apatite initiation and elongation. Coordinated
and controlled reaction between type I collagen and bone/dentin-specific noncollagenous
proteins are necessary for well defined biogenic crystal formation. However, the process by
which collagen surfaces become mineralized is not understood. Dentin matrix protein 1 …
considered to be matrix regulated. Osteoblasts and odontoblasts synthesize a polymeric
collagenous matrix, which forms a template for apatite initiation and elongation. Coordinated
and controlled reaction between type I collagen and bone/dentin-specific noncollagenous
proteins are necessary for well defined biogenic crystal formation. However, the process by
which collagen surfaces become mineralized is not understood. Dentin matrix protein 1 …
