Assessment of T-cell reactivity to the SARS-CoV-2 omicron variant by immunized individuals
L De Marco, S D'Orso, M Pirronello… - JAMA network …, 2022 - jamanetwork.com
Importance The emergence of the highly contagious Omicron variant of SARS-CoV-2 and
the findings of a significantly reduced neutralizing potency of sera from individuals with
previous SARS-CoV-2 infection or vaccination highlights the importance of studying cellular
immunity to estimate the degree of immune protection to the new SARS-CoV-2 variant.
Objective To determine T-cell reactivity to the Omicron variant in individuals with established
(natural and/or vaccine-induced) immunity to SARS-CoV-2. Design, Setting, and Participants …
the findings of a significantly reduced neutralizing potency of sera from individuals with
previous SARS-CoV-2 infection or vaccination highlights the importance of studying cellular
immunity to estimate the degree of immune protection to the new SARS-CoV-2 variant.
Objective To determine T-cell reactivity to the Omicron variant in individuals with established
(natural and/or vaccine-induced) immunity to SARS-CoV-2. Design, Setting, and Participants …
