[HTML][HTML] Activation of protein kinase B by WNT4 as a regulator of uterine leiomyoma stem cell function
Objective To investigate the functional interaction between the Wnt/β-catenin and protein
kinase B (Akt) pathways in leiomyoma stem cells (LSC). Design Laboratory study. Setting
Research laboratory. Patient (s) Premenopausal women (n= 36; age range: 28 to 49 years)
undergoing hysterectomy or myomectomy for leiomyoma. Intervention (s) None. Main
Outcome Measure (s) Gene expression, protein phosphorylation, and cell proliferation.
Result (s) Cells from human leiomyoma tissues were sorted by fluorescence-activated cell …
kinase B (Akt) pathways in leiomyoma stem cells (LSC). Design Laboratory study. Setting
Research laboratory. Patient (s) Premenopausal women (n= 36; age range: 28 to 49 years)
undergoing hysterectomy or myomectomy for leiomyoma. Intervention (s) None. Main
Outcome Measure (s) Gene expression, protein phosphorylation, and cell proliferation.
Result (s) Cells from human leiomyoma tissues were sorted by fluorescence-activated cell …